We are a family of 5 plus a 35 pound dog. I’ve always been happy with the ford crew cab based on cab room. The dodge mega cab or new body style crew cab are also roomy. I’ve owned and used 2004, 2006, 2008 gas chev 2500. 2004 diesel chev 2500. 2006 F250 & 2011 F350 ford diesel, 2011 & 2013 Ford F-250 gas. 2007, 2010 and 2013 Dodge 2500 gas.
For gas engines I’ve had experience with chev 6.0, Ford 6.2 and Dodge 5.7. I found the ford and chev quite similar for towing a 28 to 30’ holiday trailer at 6000-8000 pounds. The dodge had the least bottom end torque so was always running at high RPM. Got the job done but not as pleasant.
I like the ford manual mode for their auto transmission the best, allows to hold a gear for going up and down hills.
For Diesel engines ford 7.3 or 6.7 are most reliable. With a 6.0 or 6.4 expect to spend 6-8 grand in upgrades and deletes to get reliability. Nothing challenges a holiday like tow vehicle troubles.
For Chevy the 6.6 duramax and Allison are all pretty solid, there were some injector issues pre 2003 and 2006-2008 are the most sought after for reliability and pre emissions. Stay away from tuned duramax unless the transmission has been strengthened.
Know the least about dodge although the 5.9 Cummins is very sought after and the 6.7 after 2008 have been very good. The older dodge auto transmissions (pre 2008) are considered a weak point for heavy use.
For suspension the chevys ride the best and with a ford I’d either go to a F350 or put air bags in a F250. Also make sure whatever brand is a tow package with rear anti-sway bar.