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If you get blisters, before they pop, applying bleach to the blister will cause the body to remove the fluid and it will heal flawlessly most of the time.....
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I use a Bic Metal razor to remove thickening skin or calluses as stated by 303skier. I swear by it. The skin comes off fast and smooth.
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I use liners, gloves, and I hold the handle in my fingertips most of the time. In addition, I use a 1.09 or largest handle I can get from Brenda at in tow.
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Most of the season my hands look like I work in an office....