I like to mix asprin and NSAIDs but I don't often need them. Thing with NSAIDs is that you dont' get instant relieve like asprin, your body needs to build up a supply per say of the NSAIDs before you get benefits.
I miss the days where anything from a cold/flu to soreness could be treated with a cold beer, hot shower and a handful of pills or shot of Nyquil. Not that it doesn't still work, but I can't recover from that fix like I used to.